apalutamide will minimize the level or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of apalutamide, a solid CYP3A4 inducer, with drugs which are CYP3A4 substrates may lead to decrease publicity to these prescription drugs.When you ignore to take a dose, consider it when… Read More